Compounds > 7-(1-azepanyl)-3-(2-methoxyphenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidine
Page last updated: 2024-08-01 04:02:27

7-(1-azepanyl)-3-(2-methoxyphenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidine

Description

7-(1-azepanyl)-3-(2-methoxyphenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidine : no description available [CHeBI]

Cross-References

ID SourceID
PubMed CID4183437
CHEMBL ID1321713
CHEBI ID115673

Synonyms (12)

Synonym
REGID_FOR_CID_4183437
MLS000120260 ,
smr000097177
CHEBI:115673
7-(azepan-1-yl)-3-(2-methoxyphenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidine
HMS2256D15
CHEMBL1321713
7-(azepan-1-yl)-3-(2-methoxyphenyl)-2,5-dimethyl-pyrazolo[1,5-a]pyrimidine
7-(1-azepanyl)-3-(2-methoxyphenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidine
bdbm42175
cid_4183437
Q27198021

Drug Classes (2)

ClassDescription
ring assemblyTwo or more cyclic systems (single rings or fused systems) which are directly joined to each other by double or single bonds are named ring assemblies when the number of such direct ring junctions is one less than the number of cyclic systems involved.
pyrazoles

Protein Targets (28)

Potency Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)
Chain A, Beta-lactamaseEscherichia coli K-12Potency18.4469AID485294; AID485341
Chain A, HADH2 proteinHomo sapiens (human)Potency35.7168AID886; AID893
Chain B, HADH2 proteinHomo sapiens (human)Potency35.7168AID886; AID893
Chain A, 2-oxoglutarate OxygenaseHomo sapiens (human)Potency35.4813AID2147
glp-1 receptor, partialHomo sapiens (human)Potency28.1838AID624417
ATAD5 protein, partialHomo sapiens (human)Potency23.1093AID504467
TDP1 proteinHomo sapiens (human)Potency17.3582AID686978; AID686979
Smad3Homo sapiens (human)Potency11.2202AID588855
apical membrane antigen 1, AMA1Plasmodium falciparum 3D7Potency44.6684AID720542
PINK1Homo sapiens (human)Potency14.1254AID624263
thyroid stimulating hormone receptorHomo sapiens (human)Potency15.8489AID926; AID938
nonstructural protein 1Influenza A virus (A/WSN/1933(H1N1))Potency11.2202AID2326
67.9K proteinVaccinia virusPotency28.1838AID720579; AID720580
ParkinHomo sapiens (human)Potency14.1254AID624263
IDH1Homo sapiens (human)Potency29.0929AID686970
chromobox protein homolog 1Homo sapiens (human)Potency79.4328AID540317
nuclear factor erythroid 2-related factor 2 isoform 2Homo sapiens (human)Potency25.9290AID504444
parathyroid hormone/parathyroid hormone-related peptide receptor precursorHomo sapiens (human)Potency39.8107AID743266
huntingtin isoform 2Homo sapiens (human)Potency14.1254AID1688
mitogen-activated protein kinase 1Homo sapiens (human)Potency15.8489AID995
nuclear receptor ROR-gamma isoform 1Mus musculus (house mouse)Potency17.9008AID2546; AID2551
lethal(3)malignant brain tumor-like protein 1 isoform IHomo sapiens (human)Potency39.8107AID485360
gemininHomo sapiens (human)Potency25.9290AID624296
survival motor neuron protein isoform dHomo sapiens (human)Potency12.5893AID1458
lamin isoform A-delta10Homo sapiens (human)Potency31.6228AID1487
neuropeptide S receptor isoform AHomo sapiens (human)Potency10.0000AID1461
Glycoprotein hormones alpha chainHomo sapiens (human)Potency28.1838AID624291
Guanine nucleotide-binding protein GHomo sapiens (human)Potency21.7123AID624287; AID624288

Bioassays (7)

Assay IDTitleYearJournalArticle
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13ISSN: 1934-9300Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
ISSN: 1552-4922		Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
ISSN: 1557-8127		High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13ISSN: 1934-9300Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
ISSN: 1552-4922		Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
ISSN: 1557-8127		High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID651635Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression2022The Journal of biological chemistry, 08, Volume: 298, Issue:8
ISSN: 1083-351X
AID504810Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign2010Endocrinology, Jul, Volume: 151, Issue:7
ISSN: 1945-7170		A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13ISSN: 1934-9300Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
ISSN: 1552-4922		Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
ISSN: 1557-8127		High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID504812Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign2010Endocrinology, Jul, Volume: 151, Issue:7
ISSN: 1945-7170		A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID1745845Primary qHTS for Inhibitors of ATXN expression2022The Journal of biological chemistry, 08, Volume: 298, Issue:8
ISSN: 1083-351X

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's3 (60.00)24.3611
2020's1 (20.00)2.80

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
my 5445
0
pyridazines;
ring assembly		00low000000
famprofazone
0
pyrazoles;
ring assembly		00low000000
nafoxidine
0
benzenes;
naphthalenes;
ring assembly		00low000000
nifenazone
0
pyrazoles;
ring assembly		00low000000
1-phenyl-4-pyrazolo[3,4-d]pyrimidinamine
0
pyrazoles;
ring assembly		00low000000
ramifenazone
0
pyrazoles;
ring assembly		00low000000
4-[6-amino-3-(4-methoxyphenyl)-1-pyridazin-1-iumyl]butanoic acid
0
pyridazines;
ring assembly		00low000000
oxolamine
0
oxadiazole;
ring assembly		00low000000
imolamine
0
oxadiazole;
ring assembly		00low000000
difenzoquat
0
pyrazoles;
ring assembly		00low000000
irinotecan
0
carbamate ester;
delta-lactone;
N-acylpiperidine;
pyranoindolizinoquinoline;
ring assembly;
tertiary alcohol;
tertiary amino compound		antineoplastic agent;
apoptosis inducer;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
prodrug		00low000000
n-demethylantipyrine
0
pyrazoles;
ring assembly		00low000000
4-Formyl-antipyrine
0
pyrazoles;
ring assembly		00low000000
5-amino-1-phenyl-1H-pyrazole-4-carbonitrile
0
pyrazoles;
ring assembly		00low000000
benzpiperylone
0
pyrazoles;
ring assembly		00low000000
4-hydroxyantipyrine
0
pyrazoles;
ring assembly		00low000000
galgravin
0
aryltetrahydrofuran;
dimethoxybenzene;
lignan;
ring assembly		bone density conservation agent;
neuroprotective agent;
plant metabolite;
platelet aggregation inhibitor		00low000000
cl 218872
0
pyridazines;
ring assembly		00low000000
3-phenyl-1H-pyrazole-5-carboxylic acid
0
pyrazoles;
ring assembly		00low000000
3-(2-hydroxy-4-(1,1-dimethylheptylphenyl)cyclohexan-1-ol)
0
alkylbenzene;
ring assembly		00low000000
kolaviron
0
4'-methoxyflavanones;
biflavonoid;
dihydroflavonols;
ring assembly;
secondary alpha-hydroxy ketone		hepatoprotective agent;
plant metabolite		00low000000
cgs 20625
0
pyrazoles;
ring assembly		00low000000
chondroitin sulfate E (GalNAc4,6diS-GlcA), precursor 3
0
pyrazoles;
ring assembly		00low000000
N-tert-butyl-6-ethyl-1-phenyl-4-pyrazolo[3,4-d]pyrimidinamine
0
pyrazoles;
ring assembly		00low000000
diospyrin
0
hydroxy-1,4-naphthoquinone;
ring assembly		00low000000
4-methyl-7-phenyl-3-pyrazolo[5,1-c][1,2,4]triazinecarboxylic acid ethyl ester
0
pyrazoles;
ring assembly		00low000000
4-amino-2,6-dimethyl-5-[3-(4-methylphenyl)-1H-pyrazol-5-yl]-3-pyridazinone
0
pyrazoles;
ring assembly		00low000000
1-phenyl-4-pyrazolol
0
pyrazoles;
ring assembly		00low000000
4,5-diphenyl-1,2,3-triazole
0
benzenes;
ring assembly;
triazoles		00low000000
7-amino-2-methyl-3-phenyl-6-pyrazolo[1,5-a]pyrimidinecarbonitrile
0
pyrazoles;
ring assembly		00low000000
4-(4-hydroxy-3,5-dimethylphenyl)-2-methylphthalazin-1(2H)-one
0
pyridazines;
ring assembly		00low000000
N,N-dimethyl-6-phenyl-3-pyridazinamine
0
pyridazines;
ring assembly		00low000000
6-amino-4-(2,3-dimethoxyphenyl)-3-methyl-1-phenyl-4H-pyrano[2,3-c]pyrazole-5-carbonitrile
0
pyranopyrazole;
ring assembly		00low000000
5-(2-ethoxyphenyl)-3-(2-methoxy-6-methyl-3-pyridinyl)-1,2,4-oxadiazole
0
oxadiazole;
ring assembly		00low000000
4-[2-(3-fluorophenyl)-5-methyl-7-pyrazolo[1,5-a]pyrimidinyl]morpholine
0
pyrazoles;
ring assembly		00low000000
N-(4-chlorophenyl)-4-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinecarboxamide
0
oxadiazole;
ring assembly		00low000000
2-[[6-(3,4-dimethoxyphenyl)-3-pyridazinyl]thio]-1-(1-pyrrolidinyl)ethanone
0
pyridazines;
ring assembly		00low000000
4-[2-(3-fluorophenyl)-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazolin-9-yl]morpholine
0
pyrazoles;
ring assembly		00low000000
6-amino-4-(2,5-dimethoxyphenyl)-3-methyl-1-(4-methylphenyl)-4H-pyrano[2,3-c]pyrazole-5-carbonitrile
0
pyranopyrazole;
ring assembly		00low000000
2-[[2-(4-methoxyphenyl)-5-methyl-7-pyrazolo[1,5-a]pyrimidinyl]amino]ethanol
0
pyrazoles;
ring assembly		00low000000
4-[3-(4-fluorophenyl)-2,5,6-trimethyl-7-pyrazolo[1,5-a]pyrimidinyl]morpholine
0
pyrazoles;
ring assembly		00low000000
2-[2-[[2-[[1-(4-methoxyphenyl)-4-pyrazolo[3,4-d]pyrimidinyl]thio]-1-oxoethyl]amino]-4-thiazolyl]acetic acid ethyl ester
0
pyrazoles;
ring assembly		00low000000
LSM-34623
0
pyrazoles;
ring assembly		00low000000
2-[[6-(3,4-dimethoxyphenyl)-3-pyridazinyl]thio]-1-(4-morpholinyl)ethanone
0
pyridazines;
ring assembly		00low000000
2-[[1-(4-methylphenyl)-4-pyrazolo[3,4-d]pyrimidinyl]thio]acetic acid ethyl ester
0
pyrazoles;
ring assembly		00low000000
2-[(3-oxo-5-phenyl-1,2-dihydropyrazol-4-yl)-(3-thiophenyl)methyl]propanedinitrile
0
pyrazoles;
ring assembly		00low000000
N-[2-(1-cyclohexenyl)ethyl]-1-phenyl-4-pyrazolo[3,4-d]pyrimidinamine
0
pyrazoles;
ring assembly		00low000000
5-[(3-ethoxycarbonyl-4-thiophen-2-yl-2-thiophenyl)amino]-5-oxopentanoic acid
0
ring assembly;
thiophenes		00low000000
N-(2-oxolanylmethyl)-1-phenyl-4-pyrazolo[3,4-d]pyrimidinamine
0
pyrazoles;
ring assembly		00low000000
1-phenyl-N-(3-propan-2-yloxypropyl)-4-pyrazolo[3,4-d]pyrimidinamine
0
pyrazoles;
ring assembly		00low000000
2-[2-[[1-(4-chlorophenyl)-4-pyrazolo[3,4-d]pyrimidinyl]amino]ethoxy]ethanol
0
pyrazoles;
ring assembly		00low000000
1-(4-chlorophenyl)-N-(1-methoxypropan-2-yl)-4-pyrazolo[3,4-d]pyrimidinamine
0
pyrazoles;
ring assembly		00low000000
1-[1-(4-methoxyphenyl)-4-pyrazolo[3,4-d]pyrimidinyl]-4-piperidinecarboxamide
0
pyrazoles;
ring assembly		00low000000
2-[2-[(1-phenyl-4-pyrazolo[3,4-d]pyrimidinyl)amino]ethoxy]ethanol
0
pyrazoles;
ring assembly		00low000000
LSM-17424
0
pyrazoles;
ring assembly		00low000000
LSM-19719
0
pyrazoles;
ring assembly		00low000000
2-[2-oxo-2-[4-(4-phenyl-1-phthalazinyl)-1-piperazinyl]ethyl]isoindole-1,3-dione
0
pyridazines;
ring assembly		00low000000
LSM-28231
0
pyrazoles;
ring assembly		00low000000
2,6-dimethyl-4-(1-phenyl-4-pyrazolyl)furo[2,3-d]pyrimidine
0
pyrazoles;
ring assembly		00low000000
3-phenyl-1H-cinnolin-4-one
0
pyridazines;
ring assembly		00low000000
N-tert-butyl-2-[3-(2-chlorophenyl)-1,2,4-oxadiazol-5-yl]benzamide
0
oxadiazole;
ring assembly		00low000000
Glyceryl lactopalmitate
0
pyrazoles;
ring assembly		00low000000
3-[3-(3,4-dimethoxyphenyl)-1,2,4-oxadiazol-5-yl]-N-(3-pyridinyl)propanamide
0
oxadiazole;
ring assembly		00low000000
3-[3-(4-tert-butylphenyl)-1,2,4-oxadiazol-5-yl]-N-methylpropanamide
0
oxadiazole;
ring assembly		00low000000
3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-N-(3-methylphenyl)propanamide
0
oxadiazole;
ring assembly		00low000000
3-[3-(4-tert-butylphenyl)-1,2,4-oxadiazol-5-yl]-N-ethylpropanamide
0
oxadiazole;
ring assembly		00low000000
2-[(2,5-dimethyl-3-phenyl-7-pyrazolo[1,5-a]pyrimidinyl)thio]acetonitrile
0
pyrazoles;
ring assembly		00low000000
[2-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]phenyl]-(1-pyrrolidinyl)methanone
0
oxadiazole;
ring assembly		00low000000
7-(3,5-dimethyl-1-pyrazolyl)-5-methyl-3-phenylpyrazolo[1,5-a]pyrimidine
0
pyrazoles;
ring assembly		00low000000
5-(3,5-dimethoxyphenyl)-3-(2-methoxyphenyl)-1,2,4-oxadiazole
0
oxadiazole;
ring assembly		00low000000
6-amino-1-(4-fluorophenyl)-3-methyl-4-thiophen-2-yl-5-pyrazolo[3,4-b]pyridinecarbonitrile
0
pyrazoles;
ring assembly		00low000000
4-(3,4-dimethoxyphenyl)-3-methyl-1H-pyrazol-5-amine
0
pyrazoles;
ring assembly		00low000000
2-(4-bromophenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidine
0
pyrazoles;
ring assembly		00low000000
2-(4-bromophenyl)-4-methyl-1H-pyrazol-5-one
0
pyrazoles;
ring assembly		00low000000
1-(3-methylphenyl)-N-(2-pyridinylmethyl)-4-pyrazolo[3,4-d]pyrimidinamine
0
pyrazoles;
ring assembly		00low000000
1,3-diphenyl-4-pyrazolecarbonitrile
0
pyrazoles;
ring assembly		00low000000
N-tert-butyl-1-phenyl-4-pyrazolo[3,4-d]pyrimidinamine
0
pyrazoles;
ring assembly		00low000000
5-(4-cyclohexylphenyl)-1,2-dihydropyrazol-3-one
0
pyrazoles;
ring assembly		00low000000
2-[(dimethylamino)methyl]-4-methyl-6-(1-methylcyclohexyl)phenol
0
alkylbenzene;
ring assembly		00low000000
2-(3-oxo-2-phenyl-1H-pyrazol-5-yl)acetic acid methyl ester
0
pyrazoles;
ring assembly		00low000000
4-hydroxy-1-(4-methylphenyl)-3-pyrazolecarboxylic acid ethyl ester
0
pyrazoles;
ring assembly		00low000000
1-(4-fluorophenyl)-4-hydroxy-3-pyrazolecarboxylic acid ethyl ester
0
pyrazoles;
ring assembly		00low000000
4-(3,5-dimethyl-1-pyrazolyl)-6-methyl-1-phenylpyrazolo[3,4-d]pyrimidine
0
pyrazoles;
ring assembly		00low000000
5,7-dimethyl-2-phenylpyrazolo[1,5-a]pyrimidine
0
pyrazoles;
ring assembly		00low000000
5-(methoxymethyl)-2-phenyl-1H-pyrazolo[1,5-a]pyrimidin-7-one
0
pyrazoles;
ring assembly		00low000000
3-(4-chlorophenyl)-2,5-dimethyl-1H-pyrazolo[1,5-a]pyrimidin-7-one
0
pyrazoles;
ring assembly		00low000000
2-(5,7-dimethyl-3-phenyl-6-pyrazolo[1,5-a]pyrimidinyl)acetic acid ethyl ester
0
pyrazoles;
ring assembly		00low000000
5,7-dimethyl-2-(4-methylphenyl)pyrazolo[1,5-a]pyrimidine
0
pyrazoles;
ring assembly		00low000000
(3-methyl-1-phenyl-5-thieno[2,3-c]pyrazolyl)-(3-methyl-1-pyrazolyl)methanone
0
pyrazoles;
ring assembly		00low000000
3-(4-ethoxyphenyl)-1H-pyrazole-5-carbohydrazide
0
pyrazoles;
ring assembly		00low000000
3-chloro-6-phenyl-[1,2,4]triazolo[4,3-b]pyridazine
0
pyridazines;
ring assembly		00low000000
3-[2-(4-fluorophenyl)-5-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-6-yl]propanoic acid ethyl ester
0
pyrazoles;
ring assembly		00low000000
3-(4-methoxyphenyl)-1H-pyrazole-5-carbohydrazide
0
pyrazoles;
ring assembly		00low000000
3-phenyl-5,6,7,8-tetrahydro-1H-pyrazolo[5,1-b]quinazolin-9-one
0
pyrazoles;
ring assembly		00low000000
5-(3-chloro-4-methylphenyl)-3-pyridin-4-yl-1,2,4-oxadiazole
0
oxadiazole;
ring assembly		00low000000
7,8-dimethoxy-5-methyl-3-phenylpyrazolo[3,4-c]isoquinoline
0
pyrazoles;
ring assembly		00low000000
7,8-dimethoxy-1,5-dimethyl-3-phenylpyrazolo[3,4-c]isoquinoline
0
pyrazoles;
ring assembly		00low000000
4-[(4-chlorophenyl)thio]-5-methyl-2-phenyl-1H-pyrazol-3-one
0
pyrazoles;
ring assembly		00low000000
5-methyl-1-phenyl-4-pyrazolecarboxylic acid (4-methoxyphenyl) ester
0
pyrazoles;
ring assembly		00low000000
5-(4-methylphenyl)-2-phenyl-3-pyrazolamine
0
pyrazoles;
ring assembly		00low000000
N-(4-fluorophenyl)-1-(3-methylphenyl)-4-pyrazolo[3,4-d]pyrimidinamine
0
pyrazoles;
ring assembly		00low000000
4-methoxy-2-[3-(4-methoxyphenyl)-5-methyl-1H-pyrazol-4-yl]phenol
0
pyrazoles;
ring assembly		00low000000
5-(3,5-dimethoxyphenyl)-3-phenyl-1,2,4-oxadiazole
0
oxadiazole;
ring assembly		00low000000
3-(4-methoxyphenyl)-5-(4-methylphenyl)-1,2,4-oxadiazole
0
oxadiazole;
ring assembly		00low000000
3-(4-methoxyphenyl)-5-(2-phenylethyl)-1,2,4-oxadiazole
0
oxadiazole;
ring assembly		00low000000
4-(2,4-dimethylphenyl)-2H-phthalazin-1-one
0
pyridazines;
ring assembly		00low000000
5-amino-3-ethyl-1-phenyl-4-pyrazolecarbonitrile
0
pyrazoles;
ring assembly		00low000000
5-[(4-methylphenoxy)methyl]-3-phenyl-1,2,4-oxadiazole
0
oxadiazole;
ring assembly		00low000000
3-(2-methoxy-6-methyl-3-pyridinyl)-5-(2-methoxyphenyl)-1,2,4-oxadiazole
0
oxadiazole;
ring assembly		00low000000
1-(4-methylphenyl)sulfonyl-4-phenyl-3-pyrazolamine
0
pyrazoles;
ring assembly		00low000000
LSM-16463
0
pyrazoles;
ring assembly		00low000000
N-cyclopropyl-3-methyl-1-phenyl-5-thieno[2,3-c]pyrazolecarboxamide
0
pyrazoles;
ring assembly		00low000000
5-(3,4-diethoxyphenyl)-3-pyridin-4-yl-1,2,4-oxadiazole
0
oxadiazole;
ring assembly		00low000000
7-amino-2-(4-tert-butylphenyl)-6-pyrazolo[1,5-a]pyrimidinecarboxylic acid ethyl ester
0
pyrazoles;
ring assembly		00low000000
5-(5-bromo-2-chlorophenyl)-3-pyridin-4-yl-1,2,4-oxadiazole
0
oxadiazole;
ring assembly		00low000000
2-(4-ethoxyphenyl)-3,4-dimethyl-7-[2-(1-pyrrolidinyl)ethylthio]pyrazolo[3,4-d]pyridazine
0
pyrazoles;
ring assembly		00low000000
8-[1-(3-methylphenyl)-4-pyrazolo[3,4-d]pyrimidinyl]-1,4-dioxa-8-azaspiro[4.5]decane
0
pyrazoles;
ring assembly		00low000000
3-(4-chlorophenyl)-5-propyl-1H-pyrazolo[1,5-a]pyrimidin-7-one
0
pyrazoles;
ring assembly		00low000000
2,5-dimethyl-3-phenyl-7-pyrazolo[1,5-a]pyrimidinamine
0
pyrazoles;
ring assembly		00low000000
3-methyl-N'-(1-oxo-2-phenoxyethyl)-1-phenyl-5-thieno[2,3-c]pyrazolecarbohydrazide
0
pyrazoles;
ring assembly		00low000000
4-[(3,5-dichloro-2-hydroxyphenyl)methylamino]-1,5-dimethyl-2-phenyl-3-pyrazolone
0
pyrazoles;
ring assembly		00low000000
4-(3-bromophenyl)-2-(4-bromophenyl)-7-methylpyrazolo[3,4-d]pyridazine
0
pyridazines;
ring assembly		00low000000
4-(3-bromophenyl)-7-methyl-2-(4-methylphenyl)pyrazolo[3,4-d]pyridazine
0
pyridazines;
ring assembly		00low000000
1-(1,5-dimethyl-3-oxo-2-phenyl-4-pyrazolyl)-3-(4-methylphenyl)sulfonylurea
0
pyrazoles;
ring assembly		00low000000
N-[(3-phenyl-1,2,4-oxadiazol-5-yl)methyl]-2-thiophenecarboxamide
0
oxadiazole;
ring assembly		00low000000
N-[(3-phenyl-1,2,4-oxadiazol-5-yl)methyl]-2-(2,3,5-trimethylphenoxy)acetamide
0
oxadiazole;
ring assembly		00low000000
2-(4-hydroxyphenyl)-5-methyl-1H-pyrazol-3-one
0
pyrazoles;
ring assembly		00low000000
N-[[3-(4-fluorophenyl)-1-phenyl-4-pyrazolyl]methyl]-1-phenylmethanamine
0
pyrazoles;
ring assembly		00low000000
3-phenyl-5-[[[4-phenyl-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]thio]methyl]-1,2,4-oxadiazole
0
oxadiazole;
ring assembly		00low000000
2,5-dichloro-N-methyl-N-[[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]methyl]benzenesulfonamide
0
oxadiazole;
ring assembly		00low000000
4-(5-amino-4-phenyl-1-pyrazolyl)benzoic acid
0
pyrazoles;
ring assembly		00low000000
3-(4-bromophenyl)-5-(3,5-dimethoxyphenyl)-1,2,4-oxadiazole
0
oxadiazole;
ring assembly		00low000000
2-[4-[[4-(4-methoxyphenyl)-1-phthalazinyl]amino]phenyl]acetamide
0
pyridazines;
ring assembly		00low000000
N-(3,4-dimethoxyphenyl)-1-(3-methylphenyl)-4-pyrazolo[3,4-d]pyrimidinamine
0
pyrazoles;
ring assembly		00low000000
LSM-28273
0
pyrazoles;
ring assembly		00low000000
N'-[2-[[1-(4-methylphenyl)-4-pyrazolo[3,4-d]pyrimidinyl]thio]-1-oxoethyl]-2-furancarbohydrazide
0
pyrazoles;
ring assembly		00low000000
4-morpholinyl-[4-[3-[4-(4-morpholinylsulfonyl)phenyl]-1,2,4-oxadiazol-5-yl]-1-piperidinyl]methanone
0
oxadiazole;
ring assembly		00low000000
2-[(4-chlorophenyl)methyl]-6-phenyl-5-(1-piperidinyl)-3-pyridazinone
0
pyridazines;
ring assembly		00low000000
2-[(3-chlorophenyl)methyl]-6-phenyl-5-(1-piperidinyl)-3-pyridazinone
0
pyridazines;
ring assembly		00low000000
6-phenyl-5-(1-piperidinyl)-2-prop-2-enyl-3-pyridazinone
0
pyridazines;
ring assembly		00low000000
5-(6-chloro-3-pyridinyl)-3-(3-methoxyphenyl)-1,2,4-oxadiazole
0
oxadiazole;
ring assembly		00low000000
1-methyl-5-[(4-methylphenyl)thio]-3-phenyl-4-pyrazolecarbonitrile
0
pyrazoles;
ring assembly		00low000000
3-phenyl-6-(trifluoromethyl)-1H-pyrazolo[4,3-b]pyridine
0
pyrazoles;
ring assembly		00low000000
4-(2,5-dimethoxyphenyl)-3-[3-(4-methoxyphenyl)-1H-pyrazol-5-yl]-1H-1,2,4-triazole-5-thione
0
pyrazoles;
ring assembly		00low000000
5-tert-butyl-3-(4-chlorophenyl)-N-(2-pyridinylmethyl)-7-pyrazolo[1,5-a]pyrimidinamine
0
pyrazoles;
ring assembly		00low000000
N-[2-methoxy-5-(3-methyl-4-oxo-1-phthalazinyl)phenyl]-2-(4-methylphenoxy)acetamide
0
pyridazines;
ring assembly		00low000000
LSM-20639
0
pyrazoles;
ring assembly		00low000000
6-[[(4-chlorophenyl)thio]methyl]-2-phenyl-1,7-dihydropyrazolo[3,4-b]pyridine-3,4-dione
0
pyrazoles;
ring assembly		00low000000
N-(3,4-dichlorophenyl)-2-[4-(4-methoxyphenyl)-1-oxo-2-phthalazinyl]acetamide
0
pyridazines;
ring assembly		00low000000
4-(2,5-dimethoxyphenyl)-3-(3-phenyl-1H-pyrazol-5-yl)-1H-1,2,4-triazole-5-thione
0
pyrazoles;
ring assembly		00low000000
N-[5-methyl-2-(4-methylphenyl)-3-pyrazolyl]-2-[(7-methyl-4-oxo-2,3-dihydro-1H-cyclopenta[c][1]benzopyran-9-yl)oxy]acetamide
0
pyrazoles;
ring assembly		00low000000
5-tert-butyl-2-methyl-3-phenyl-N-(2-pyridinylmethyl)-7-pyrazolo[1,5-a]pyrimidinamine
0
pyrazoles;
ring assembly		00low000000
1-(4-methoxyphenyl)-N-[2-(4-morpholinyl)ethyl]-4-pyrazolo[3,4-d]pyrimidinamine
0
pyrazoles;
ring assembly		00low000000
N-(5-tert-butyl-2-phenyl-3-pyrazolyl)-2-[(6-methyl-1H-benzimidazol-2-yl)thio]acetamide
0
pyrazoles;
ring assembly		00low000000
N-(1,5-dimethyl-3-oxo-2-phenyl-4-pyrazolyl)-3-(2-methylphenoxy)propanamide
0
pyrazoles;
ring assembly		00low000000
N-(1,3-benzodioxol-5-ylmethyl)-2-[(3-methyl-4-oxo-5-thiophen-2-yl-2-thieno[2,3-d]pyrimidinyl)thio]acetamide
0
ring assembly;
thiophenes		00low000000
N-[4-(4-methyl-2-thiazolyl)-2-phenyl-3-pyrazolyl]-3-(trifluoromethyl)benzamide
0
pyrazoles;
ring assembly		00low000000
1-(4-fluorophenyl)-3-methyl-5-thieno[2,3-c]pyrazolecarboxylic acid [2-(methylamino)-2-oxoethyl] ester
0
pyrazoles;
ring assembly		00low000000
2-chloro-N-[3-(4-methylphenyl)-1-phenyl-4-pyrazolyl]acetamide
0
pyrazoles;
ring assembly		00low000000
3-(4-methoxyphenyl)-1-phenyl-4-pyrazolamine
0
pyrazoles;
ring assembly		00low000000
N-(5-cyclopropyl-1,3,4-thiadiazol-2-yl)-2,5-diphenyl-3-pyrazolecarboxamide
0
pyrazoles;
ring assembly		00low000000
2-chloro-N-(2-phenyl-5-propyl-3-pyrazolyl)acetamide
0
pyrazoles;
ring assembly		00low000000
2-[[1-oxo-2-(1H-1,2,4-triazol-5-ylthio)ethyl]amino]-4-thiophen-2-yl-3-thiophenecarboxylic acid ethyl ester
0
ring assembly;
thiophenes		00low000000
3-(2-chlorophenyl)-N-cyclohexyl-5-methyl-N-[(3-phenyl-1,2,4-oxadiazol-5-yl)methyl]-4-isoxazolecarboxamide
0
oxadiazole;
ring assembly		00low000000
N-(5-methyl-2-phenyl-3-pyrazolyl)-2-phenoxyacetamide
0
pyrazoles;
ring assembly		00low000000
1-phenyl-N-(3-pyridinylmethyl)-3-thiophen-2-yl-4-pyrazolecarboxamide
0
pyrazoles;
ring assembly		00low000000
N-[[2-(diethylamino)ethylamino]-sulfanylidenemethyl]-3-(4-methoxyphenyl)-1-phenyl-4-pyrazolecarboxamide
0
pyrazoles;
ring assembly		00low000000
3-(4-methoxyphenyl)-N-[[[oxo(pyridin-4-yl)methyl]hydrazo]-sulfanylidenemethyl]-1-phenyl-4-pyrazolecarboxamide
0
pyrazoles;
ring assembly		00low000000
3-methyl-N,1-diphenyl-4-pyrazolecarbothioamide
0
pyrazoles;
ring assembly		00low000000
1-(2-chlorophenyl)-N-(5-cyclopropyl-1,3,4-thiadiazol-2-yl)-3-methyl-5-thieno[2,3-c]pyrazolecarboxamide
0
pyrazoles;
ring assembly		00low000000
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-(3,5-dimethyl-1-pyrazolyl)benzamide
0
pyrazoles;
ring assembly		00low000000
3-[2-[(1,5-dimethyl-3-oxo-2-phenyl-4-pyrazolyl)amino]-2-oxoethyl]-4-oxo-1-phthalazinecarboxylic acid
0
pyrazoles;
ring assembly		00low000000
5-(4-propylphenyl)-1H-pyrazol-3-amine
0
pyrazoles;
ring assembly		00low000000
N-(1,5-dimethyl-3-oxo-2-phenyl-4-pyrazolyl)-2-[(6-methyl-1H-benzimidazol-2-yl)thio]acetamide
0
pyrazoles;
ring assembly		00low000000
3-methyl-1-phenyl-5-thieno[2,3-c]pyrazolecarboxylic acid [2-(butylamino)-2-oxoethyl] ester
0
pyrazoles;
ring assembly		00low000000
N2-[5-(4-chlorophenyl)-2-phenyl-3-pyrazolyl]benzene-1,2-diamine
0
pyrazoles;
ring assembly		00low000000
N2-[2-(4-methylphenyl)-5-phenyl-3-pyrazolyl]benzene-1,2-diamine
0
pyrazoles;
ring assembly		00low000000
N2-(5-phenyl-1H-pyrazol-3-yl)benzene-1,2-diamine
0
pyrazoles;
ring assembly		00low000000
2-phenyl-5-thiophen-2-yl-3-pyrazolecarboxylic acid [2-(3-nitroanilino)-2-oxoethyl] ester
0
pyrazoles;
ring assembly		00low000000
2-phenyl-5-thiophen-2-yl-3-pyrazolecarboxylic acid [2-(2-chloro-5-nitroanilino)-2-oxoethyl] ester
0
pyrazoles;
ring assembly		00low000000
2-phenyl-5-thiophen-2-yl-3-pyrazolecarboxylic acid [2-(4-chloro-3-nitroanilino)-2-oxoethyl] ester
0
pyrazoles;
ring assembly		00low000000
N-[[(4-oxo-1-phenyl-5-pyrazolo[3,4-d]pyrimidinyl)amino]-sulfanylidenemethyl]benzamide
0
pyrazoles;
ring assembly		00low000000
N2-[5-(3-chlorophenyl)-2-phenyl-3-pyrazolyl]benzene-1,2-diamine
0
pyrazoles;
ring assembly		00low000000
2-phenyl-5-sulfanylidene-3,7,8,9,10,11-hexahydropyrazolo[4,5]pyrimido[3,5-a]azepin-1-one
0
pyrazoles;
ring assembly		00low000000
3-(3,4-dimethylphenyl)-1-(phenylmethyl)-4-pyrazolecarboxaldehyde
0
pyrazoles;
ring assembly		00low000000
4-(3-methyl-1-phenyl-1H-pyrazolo[3,4-b]quinolin-4-yl)morpholine
0
pyrazoles;
ring assembly		00low000000
N,N-diethyl-5-thiophen-2-yl-2-thiophenecarboxamide
0
ring assembly;
thiophenes		00low000000
2,5-bis(3,5-dimethyl-1-phenyl-4-pyrazolyl)-1,3,4-oxadiazole
0
pyrazoles;
ring assembly		00low000000
4-(3-methylphenyl)-2-(3-nitrophenyl)-3-pyrazolamine
0
pyrazoles;
ring assembly		00low000000
4-(4-methylphenyl)-2-(3-nitrophenyl)-3-pyrazolamine
0
pyrazoles;
ring assembly		00low000000
3-(2,4-dichlorophenyl)-1,4,5,6-tetrahydrocyclopenta[c]pyrazole
0
pyrazoles;
ring assembly		00low000000
2-(3,5-dimethyl-1-pyrazolyl)benzonitrile
0
pyrazoles;
ring assembly		00low000000
sc 514
0
ring assembly;
thiophenes		00low000000
5-(2,3-dihydrobenzofuran-5-yl)-3-(4-fluorophenyl)-1,2,4-oxadiazole
0
oxadiazole;
ring assembly		00low000000
1-(4-fluorophenyl)-3-[4-(4-fluorophenyl)-2-methyl-5-(trifluoromethyl)-3-pyrazolyl]urea
0
pyrazoles;
ring assembly		00low000000
3,3-dimethyl-5-oxo-5-[(3-phenyl-1H-pyrazol-5-yl)amino]pentanoic acid
0
pyrazoles;
ring assembly		00low000000
1-[(4-chlorophenyl)-oxomethyl]-5-hydroxy-5-phenyl-4H-pyrazole-3-carboxylic acid methyl ester
0
pyrazoles;
ring assembly		00low000000
6-amino-4-(2-methylpropyl)-3-phenyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
0
pyranopyrazole;
ring assembly		00low000000
1,3,8-trimethyl-5,10-diphenylpyrimido[1,2]pyrrolo[4,5-b]pyridazine-2,4-dione
0
pyridazines;
ring assembly		00low000000
5-[[(1-cyclohexyl-5-tetrazolyl)thio]methyl]-3-phenyl-1,2,4-oxadiazole
0
oxadiazole;
ring assembly		00low000000
4-(5-methyl-3-oxo-1H-pyrazol-2-yl)benzoic acid
0
pyrazoles;
ring assembly		00low000000
4-[1-(4-chlorophenyl)-4-pyrazolo[3,4-d]pyrimidinyl]-2,6-dimethylmorpholine
0
pyrazoles;
ring assembly		00low000000
1-(4-methoxyphenyl)-N,N-dipropyl-4-pyrazolo[3,4-d]pyrimidinamine
0
pyrazoles;
ring assembly		00low000000
2-(1,5-dimethyl-3-oxo-2-phenyl-4-pyrazolyl)-3-hydroxy-3-phenyl-1-isoindolone
0
pyrazoles;
ring assembly		00low000000
2-(1,3-diphenyl-4-pyrazolyl)-3-(2-furanylmethyl)-4-thiazolidinone
0
pyrazoles;
ring assembly		00low000000
3-(4-fluorophenyl)-N-[3-(1-imidazolyl)propyl]-1-phenyl-4-pyrazolecarboxamide
0
pyrazoles;
ring assembly		00low000000
1-(4-fluorophenyl)-3-methyl-5-thieno[2,3-c]pyrazolecarboxylic acid (2-oxo-3-oxolanyl) ester
0
pyrazoles;
ring assembly		00low000000
3,5-dimethyl-1-phenyl-4-pyrazolecarboxylic acid [2-[4-amino-1-methyl-3-(2-methylpropyl)-2,6-dioxo-5-pyrimidinyl]-2-oxoethyl] ester
0
pyrazoles;
ring assembly		00low000000
4-methyl-3-phenyl-1H-pyrazole-5-carbohydrazide
0
pyrazoles;
ring assembly		00low000000
3-(4-fluorophenyl)-5-(2-furanyl)-2-phenyl-3,4-dihydropyrazole
0
pyrazoles;
ring assembly		00low000000
6-amino-4-(3-furanyl)-3-(4-methoxyphenyl)-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
0
pyranopyrazole;
ring assembly		00low000000
1-[3-[3-(3-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]-1-butanone
0
oxadiazole;
ring assembly		00low000000
7-(2-ethyl-1-piperidinyl)-5-methyl-2-(3-methylphenyl)pyrazolo[1,5-a]pyrimidine
0
pyrazoles;
ring assembly		00low000000
N-(2,4-dimethoxyphenyl)-2-[1-(3,4-dimethylphenyl)-4-oxo-5-pyrazolo[3,4-d]pyrimidinyl]acetamide
0
pyrazoles;
ring assembly		00low000000
3-[3-(4-methylphenyl)-6-oxo-1-pyridazinyl]-N-[2-(2-methyl-1-piperidinyl)ethyl]propanamide
0
pyridazines;
ring assembly		00low000000
N-[2-(2,4-dimethylphenyl)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-1,3-benzodioxole-5-carboxamide
0
pyrazoles;
ring assembly		00low000000
2-(2-methoxyphenyl)-N-[4-[5-(3-methoxyphenyl)-1,2,4-oxadiazol-3-yl]phenyl]acetamide
0
oxadiazole;
ring assembly		00low000000
4-morpholinecarboxylic acid [4-[6-amino-5-cyano-3-(4-methylphenyl)-2,4-dihydropyrano[2,3-c]pyrazol-4-yl]phenyl] ester
0
pyranopyrazole;
ring assembly		00low000000
N-(3-chlorophenyl)-2-[1-(3,4-dimethylphenyl)-4-oxo-5-pyrazolo[3,4-d]pyrimidinyl]acetamide
0
pyrazoles;
ring assembly		00low000000
1-(4-chlorophenyl)-5-[1-[(2-methylpropan-2-yl)oxy-oxomethyl]-4-piperidinyl]-4-pyrazolecarboxylic acid
0
pyrazoles;
ring assembly		00low000000
N-[2-(2,3-dimethylphenyl)-5,5-dioxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-2-methoxybenzamide
0
pyrazoles;
ring assembly		00low000000
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]propanamide
0
oxadiazole;
ring assembly		00low000000
3-(4-bromophenyl)-1H-pyrazole-5-carboxylic acid methyl ester
0
pyrazoles;
ring assembly		00low000000
5-methyl-N-(5-methyl-2-phenyl-3-pyrazolyl)-3-isoxazolecarboxamide
0
pyrazoles;
ring assembly		00low000000
2-(4-ethoxyphenyl)-5-[1-[(2-methylpropan-2-yl)oxy-oxomethyl]-4-piperidinyl]-6-pyrazolo[1,5-a]pyrimidinecarboxylic acid
0
pyrazoles;
ring assembly		00low000000
3-[5-amino-3-(4-chlorophenyl)-1-pyrazolyl]propanoic acid ethyl ester
0
pyrazoles;
ring assembly		00low000000
2-(4-methoxyphenyl)-N-[4-[5-(3,4,5-trimethoxyphenyl)-1,2,4-oxadiazol-3-yl]phenyl]acetamide
0
oxadiazole;
ring assembly		00low000000
N-(5-chloro-2,4-dimethoxyphenyl)-3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]propanamide
0
oxadiazole;
ring assembly		00low000000
N-ethyl-3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]-N-(phenylmethyl)propanamide
0
oxadiazole;
ring assembly		00low000000
N-[2-(dimethylamino)ethyl]-2-[3-(4-methylphenyl)-6-oxo-1-pyridazinyl]acetamide
0
pyridazines;
ring assembly		00low000000
3-methyl-N-[2-(4-morpholinyl)ethyl]-1-phenyl-5-thieno[2,3-c]pyrazolecarboxamide
0
pyrazoles;
ring assembly		00low000000
3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)propanamide
0
oxadiazole;
ring assembly		00low000000
N-[2-(3,4-dihydro-1H-isoquinolin-2-yl)ethyl]-3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]propanamide
0
oxadiazole;
ring assembly		00low000000
N-ethyl-N-(2-ethylphenyl)-3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]propanamide
0
oxadiazole;
ring assembly		00low000000
6-amino-4-methyl-3-(4-methylphenyl)-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
0
pyranopyrazole;
ring assembly		00low000000
1,3-diphenyl-4-pyrazolecarboxylic acid [2-[(3,5-dichloro-2-pyridinyl)amino]-2-oxoethyl] ester
0
pyrazoles;
ring assembly		00low000000
4-[3-(1,3-diphenyl-4-pyrazolyl)-5-thiophen-2-yl-3,4-dihydropyrazol-2-yl]-4-oxobutanoic acid
0
pyrazoles;
ring assembly		00low000000
gtp 14564
0
pyrazoles;
ring assembly		00low000000
2-amino-7,7-dimethyl-5-oxo-4-[1-phenyl-3-(4-propan-2-ylphenyl)-4-pyrazolyl]-6,8-dihydro-4H-1-benzopyran-3-carbonitrile
0
pyrazoles;
ring assembly		00low000000
N-[4-[5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl]phenyl]-2-(4-methoxyphenyl)acetamide
0
oxadiazole;
ring assembly		00low000000
5-[3-[3-(4-methoxyphenyl)-1-phenyl-4-pyrazolyl]-5-thiophen-2-yl-3,4-dihydropyrazol-2-yl]-5-oxopentanoic acid
0
pyrazoles;
ring assembly		00low000000
4-[1-(4-bromophenyl)-2-nitroethyl]-5-methyl-2-phenyl-1H-pyrazol-3-one
0
pyrazoles;
ring assembly		00low000000
3-ethyl-2-sulfanylidene-5-thiophen-2-yl-1H-thieno[2,3-d]pyrimidin-4-one
0
ring assembly;
thiophenes		00low000000
5-chloro-4-[methoxy(phenyl)methyl]-1-methyl-3-phenylpyrazole
0
pyrazoles;
ring assembly		00low000000
6-amino-3-(3-methoxyphenyl)-4-(3-thiophenyl)-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
0
pyranopyrazole;
ring assembly		00low000000
5-methyl-3-phenyl-7-(prop-2-enylthio)pyrazolo[1,5-a]pyrimidine
0
pyrazoles;
ring assembly		00low000000
2-[4-[3-(4-methoxyphenyl)-1H-pyrazol-5-yl]-1-piperidinyl]-3-nitropyridine
0
pyrazoles;
ring assembly		00low000000
2-[(2,6-dichlorophenyl)methyl]-6-phenyl-5-(1-piperidinyl)-3-pyridazinone
0
pyridazines;
ring assembly		00low000000
2-[[1-(4-chlorophenyl)-4-pyrazolo[3,4-d]pyrimidinyl]amino]-1-butanol
0
pyrazoles;
ring assembly		00low000000
4-[(2-hydroxy-3-nitrophenyl)-(5-methyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methyl]-5-methyl-2-phenyl-1H-pyrazol-3-one
0
pyrazoles;
ring assembly		00low000000
N-butan-2-yl-2-[[3-(1,5-dimethyl-3-oxo-2-phenyl-4-pyrazolyl)-4-oxo-2-quinazolinyl]thio]acetamide
0
pyrazoles;
ring assembly		00low000000
3-(5-bromo-2-furanyl)-5-(4-methoxyphenyl)-1,2,4-oxadiazole
0
oxadiazole;
ring assembly		00low000000
sew2871
0
oxadiazole;
ring assembly		00low000000
5-methyl-4-[(5-methyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-(3-nitrophenyl)methyl]-2-phenyl-1H-pyrazol-3-one
0
pyrazoles;
ring assembly		00low000000
4-(3,5-dimethyl-1-pyrazolyl)benzoic acid [2-(4-chloro-2-nitroanilino)-2-oxoethyl] ester
0
pyrazoles;
ring assembly		00low000000
am 281
0
pyrazoles;
ring assembly		00low000000
LSM-28389
0
pyrazoles;
ring assembly		00low000000
LSM-16826
0
pyrazoles;
ring assembly		00low000000
1-(4-methoxyphenyl)-N-(2-oxolanylmethyl)-4-pyrazolo[3,4-d]pyrimidinamine
0
pyrazoles;
ring assembly		00low000000
3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol
0
alkylbenzene;
ring assembly		00low000000
4-[1-(4-fluorophenyl)-2-nitroethyl]-5-methyl-2-phenyl-1H-pyrazol-3-one
0
pyrazoles;
ring assembly		00low000000
6-amino-4-(3,5-dimethyl-1-phenyl-4-pyrazolyl)-3-methyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
0
pyranopyrazole;
ring assembly		00low000000
3-(4-ethoxyphenyl)-N-[(1-methyl-4-piperidinylidene)amino]-1H-pyrazole-5-carboxamide
0
pyrazoles;
ring assembly		00low000000
6-[5-chloro-3-methyl-1-(4-methylphenyl)-4-pyrazolyl]-3,4-dimethyl-2-oxo-1,6-dihydropyrimidine-5-carboxylic acid ethyl ester
0
pyrazoles;
ring assembly		00low000000
N-[3-(1-imidazolyl)propyl]-2-methyl-3-phenyl-5-propyl-7-pyrazolo[1,5-a]pyrimidinamine
0
pyrazoles;
ring assembly		00low000000
5-tert-butyl-3-(4-chlorophenyl)-7-(2-ethyl-1-imidazolyl)pyrazolo[1,5-a]pyrimidine
0
pyrazoles;
ring assembly		00low000000
3-(3,4-dimethoxyphenyl)-1,2,4-oxadiazole-5-carboxylic acid ethyl ester
0
oxadiazole;
ring assembly		00low000000
4-[1-(2,4-dichlorophenyl)-2-nitroethyl]-5-(2-hydroxyphenyl)-1,2-dihydropyrazol-3-one
0
pyrazoles;
ring assembly		00low000000
[5-(4-chlorophenyl)-1-(3,4-dichlorophenyl)-3-pyrazolyl]-(4-morpholinyl)methanone
0
pyrazoles;
ring assembly		00low000000
4-[3-(2-chloro-1-oxoethyl)-2,5-dimethyl-1-pyrrolyl]-1,5-dimethyl-2-phenyl-3-pyrazolone
0
pyrazoles;
ring assembly		00low000000
6-amino-1,3-diphenyl-4-(3,4,5-trimethoxyphenyl)-4H-pyrano[2,3-c]pyrazole-5-carbonitrile
0
pyranopyrazole;
ring assembly		00low000000
ginkgetin
0
biflavonoid;
hydroxyflavone;
methoxyflavone;
ring assembly		anti-HSV-1 agent;
antineoplastic agent;
cyclooxygenase 2 inhibitor;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
metabolite		00low000000
amentoflavone
0
biflavonoid;
hydroxyflavone;
ring assembly		angiogenesis inhibitor;
antiviral agent;
cathepsin B inhibitor;
P450 inhibitor;
plant metabolite		00low000000
cupressuflavone
0
biflavonoid;
hydroxyflavone;
ring assembly		EC 3.4.21.37 (leukocyte elastase) inhibitor;
metabolite;
radical scavenger		00low000000
robustaflavone
0
biflavonoid;
hydroxyflavone;
ring assembly		anti-HBV agent;
antineoplastic agent;
antioxidant;
metabolite		00low000000
sciadopitysin
0
biflavonoid;
hydroxyflavone;
methoxyflavone;
ring assembly		bone density conservation agent;
platelet aggregation inhibitor		00low000000
2-(4-fluoro-3-methylphenyl)sulfonyl-5-(2-methoxyphenyl)-3-pyrazolamine
0
pyrazoles;
ring assembly		00low000000
4-[[[3-(2-fluorophenyl)-1-methyl-5-thieno[2,3-c]pyrazolyl]-oxomethyl]amino]-1-piperidinecarboxylic acid ethyl ester
0
pyrazoles;
ring assembly		00low000000
3-(4-chlorophenyl)-N-cyclopropyl-1-methyl-5-thieno[2,3-c]pyrazolecarboxamide
0
pyrazoles;
ring assembly		00low000000
3-(4-chlorophenyl)-1-methyl-N-[(5-methyl-2-furanyl)methyl]-5-thieno[2,3-c]pyrazolecarboxamide
0
pyrazoles;
ring assembly		00low000000
N-(1,5-dimethyl-3-oxo-2-phenyl-4-pyrazolyl)-1-(1H-imidazol-5-ylsulfonyl)-3-piperidinecarboxamide
0
pyrazoles;
ring assembly		00low000000
3-(4-chlorophenyl)-1-methyl-N-[3-(1-pyrrolidinyl)propyl]-5-thieno[2,3-c]pyrazolecarboxamide
0
pyrazoles;
ring assembly		00low000000
4-[3-(4-fluorophenyl)-2-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl]-1-piperidinecarboxylic acid ethyl ester
0
pyrazoles;
ring assembly		00low000000
5-chloro-2-methoxy-N-[[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]methyl]-N-propan-2-ylbenzamide
0
oxadiazole;
ring assembly		00low000000
N-(6-acetyl-1,3-benzodioxol-5-yl)-5-methyl-2-phenyl-3-pyrazolecarboxamide
0
pyrazoles;
ring assembly		00low000000
3-(4-chlorophenyl)-N-[2-(diethylamino)ethyl]-1-methyl-5-thieno[2,3-c]pyrazolecarboxamide
0
pyrazoles;
ring assembly		00low000000
vinorelbine
0
acetate ester;
methyl ester;
organic heteropentacyclic compound;
organic heterotetracyclic compound;
ring assembly;
vinca alkaloid		antineoplastic agent;
photosensitizing agent		00low000000
HTS 01037
0
ring assembly;
thiophenes		00low000000
4,5-diphenyl-2,3-dihydro-1H-pyrazolo[3,4-c]pyridazin-3-one
0
pyridazines;
ring assembly		00low000000
1-(3,4-dimethylphenyl)-4-(4-methyl-1-piperidinyl)phthalazine
0
pyridazines;
ring assembly		00low000000
2-(4-nitrophenoxy)-1-[4-(4-phenyl-1-phthalazinyl)-1-piperazinyl]ethanone
0
pyridazines;
ring assembly		00low000000
3-amino-5-(4-bromophenyl)-4-pyridazinecarbonitrile
0
pyridazines;
ring assembly		00low000000
acuminatin
0
1-benzofurans;
dimethoxybenzene;
neolignan;
olefinic compound;
ring assembly		fungal metabolite;
plant metabolite		00low000000
N,2-dimethyl-N-[(3-phenyl-1,2,4-oxadiazol-5-yl)methyl]-3-furancarboxamide
0
oxadiazole;
ring assembly		00low000000
2-(4-methoxyphenyl)-5-[1-[(2-methylpropan-2-yl)oxy-oxomethyl]-4-piperidinyl]-6-pyrazolo[1,5-a]pyrimidinecarboxylic acid ethyl ester
0
pyrazoles;
ring assembly		00low000000
N-cyclohexyl-2-[[6-(4-ethoxyphenyl)-3-pyridazinyl]thio]acetamide
0
pyridazines;
ring assembly		00low000000
N-(5-methyl-3-isoxazolyl)-2-[[6-(4-methylphenyl)-3-pyridazinyl]thio]acetamide
0
pyridazines;
ring assembly		00low000000
n-(4-methylthiazol-2-yl)-2-(6-phenylpyridazin-3-ylthio)acetamide
0
pyridazines;
ring assembly		00low000000
N-[4-([1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl]cyclohexanecarboxamide
0
pyridazines;
ring assembly		00low000000
6-(4-ethylphenyl)-3-(methylthio)-[1,2,4]triazolo[4,3-b]pyridazine
0
pyridazines;
ring assembly		00low000000
N-(phenylmethyl)-3-[3,4,6-trimethyl-1-(4-methylphenyl)-5-pyrazolo[3,4-b]pyridinyl]propanamide
0
pyrazoles;
ring assembly		00low000000
2-(2,1,3-benzothiadiazol-4-ylsulfonyl)-5-(4-chlorophenyl)-3-pyrazolamine
0
pyrazoles;
ring assembly		00low000000
o-demethyltramadol
0
alkylbenzene;
ring assembly		00low000000
sr 147778
0
pyrazoles;
ring assembly		00low000000
ethiprole
0
pyrazoles;
ring assembly		00low000000
1-(2,4-dichlorophenyl)-6-methyl-N-(1-piperidinyl)-4H-indeno[1,2-c]pyrazole-3-carboxamide
0
pyrazoles;
ring assembly		00low000000
ws-5995 c
0
benzenes;
naphthalenes;
ring assembly		00low000000
cc 401
0
pyrazoles;
ring assembly		00low000000
4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol
0
pyrazoles;
ring assembly		00low000000
ptc 124
0
oxadiazole;
ring assembly		00low000000
fr 180204
0
pyrazoles;
ring assembly		00low000000
n-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1h-pyrazole-4-carboxamide
0
aromatic amide;
cyclopropanes;
organofluorine compound;
pyrazoles;
ring assembly		00low000000
trametinib
0
acetamides;
aromatic amine;
cyclopropanes;
organofluorine compound;
organoiodine compound;
pyridopyrimidine;
ring assembly		anticoronaviral agent;
antineoplastic agent;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
geroprotector		00low000000
2-(2,1,3-benzothiadiazol-4-ylsulfonyl)-5-(4-bromophenyl)-3-pyrazolamine
0
pyrazoles;
ring assembly		00low000000
dactolisib
0
imidazoquinoline;
nitrile;
quinolines;
ring assembly;
ureas		antineoplastic agent;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
mTOR inhibitor		00low000000
pyriprole
0
pyrazoles;
ring assembly		00low000000
3-[2-(4-chlorophenyl)-5,7-dimethyl-6-pyrazolo[1,5-a]pyrimidinyl]-N-[1-(2,3-dihydro-1,4-benzodioxin-6-yl)ethyl]propanamide
0
pyrazoles;
ring assembly		00low000000
macitentan
0
aromatic ether;
organobromine compound;
pyrimidines;
ring assembly;
sulfamides		antihypertensive agent;
endothelin receptor antagonist;
orphan drug		00low000000
3-[2-(3,5-dimethoxyphenyl)-5,7-dimethyl-6-pyrazolo[1,5-a]pyrimidinyl]-N-(phenylmethyl)propanamide
0
pyrazoles;
ring assembly		00low000000
[3-(4-bromophenyl)-1H-pyrazol-5-yl]-[4-(3,4-dimethoxyphenyl)sulfonyl-1-piperazinyl]methanone
0
pyrazoles;
ring assembly		00low000000
3-[3-(4-fluorophenyl)-2,5,7-trimethyl-6-pyrazolo[1,5-a]pyrimidinyl]-N-(2-methoxyphenyl)propanamide
0
pyrazoles;
ring assembly		00low000000
N-[[3-(2-chlorophenyl)-1-(4-fluorophenyl)-4-pyrazolyl]methyl]-2-(2-pyridinyl)ethanamine
0
pyrazoles;
ring assembly		00low000000
(3aS,5S,9aS)-5-[1-(2-methoxyphenyl)-4-pyrazolyl]-2-phenyl-3a,4,5,7,8,9-hexahydro-3H-pyrrolo[3,4-h]pyrrolizin-1-one
0
pyrazoles;
ring assembly		00low000000
1-[[3-(3-fluorophenyl)-1-(4-methoxyphenyl)-4-pyrazolyl]methyl]-4-methoxypiperidine
0
pyrazoles;
ring assembly		00low000000
N-[[5-(2,4-difluorophenyl)-1H-pyrazol-4-yl]methyl]-1-(3-thiophenyl)-2-propanamine
0
pyrazoles;
ring assembly		00low000000
N-[[3-(3-methylphenyl)-1-(4-methylphenyl)-4-pyrazolyl]methyl]-3-(1-pyrazolyl)-1-propanamine
0
pyrazoles;
ring assembly		00low000000
1-(1,5-dimethyl-3-pyrazolyl)-N-[[5-(2-fluoro-4-methoxyphenyl)-1H-pyrazol-4-yl]methyl]methanamine
0
pyrazoles;
ring assembly		00low000000
(1R,5S)-6-[[5-(2-fluoro-4-methoxyphenyl)-1H-pyrazol-4-yl]methyl]-6-azabicyclo[3.2.1]octane
0
pyrazoles;
ring assembly		00low000000
1-[[3-(4-fluorophenyl)-1-(4-methylphenyl)-4-pyrazolyl]methyl]-4-[(1-methyl-2-imidazolyl)methyl]piperazine
0
pyrazoles;
ring assembly		00low000000
(3aS,5S,9aS)-2-[(2-methylphenyl)methyl]-5-(1-methyl-3-phenyl-4-pyrazolyl)-3a,4,5,7,8,9-hexahydro-3H-pyrrolo[3,4-h]pyrrolizin-1-one
0
pyrazoles;
ring assembly		00low000000
1-ethyl-4-[[methyl-[[3-[4-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl]methyl]amino]methyl]-2-pyrrolidinone
0
oxadiazole;
ring assembly		00low000000
2-(3,5-dimethyl-1-pyrazolyl)-N-[[3-(4-fluorophenyl)-1-(4-methylphenyl)-4-pyrazolyl]methyl]ethanamine
0
pyrazoles;
ring assembly		00low000000
1-[[3-(2-fluorophenyl)-1-methyl-4-pyrazolyl]methyl]-3-propoxypiperidine
0
pyrazoles;
ring assembly		00low000000
N'-[1-(3,4-dimethylphenyl)-4-pyrazolo[3,4-d]pyrimidinyl]acetohydrazide
0
pyrazoles;
ring assembly		00low000000
5-(4-chlorophenyl)-2-(4-methoxyphenyl)sulfonyl-3-pyrazolamine
0
pyrazoles;
ring assembly		00low000000
1-hydroxy-2-(5-phenyl-1H-pyrazol-3-yl)-4H-1,2,4-benzotriazin-3-one
0
pyrazoles;
ring assembly		00low000000
2-[[6-(4-ethylphenyl)-3-pyridazinyl]thio]-N-(2-oxolanylmethyl)acetamide
0
pyridazines;
ring assembly		00low000000
2-[[1-(4-fluorophenyl)-4-pyrazolo[3,4-d]pyrimidinyl]thio]-N-(2-oxolanylmethyl)acetamide
0
pyrazoles;
ring assembly		00low000000
N-[3-[6-(1-azepanyl)-3-pyridazinyl]phenyl]-4-methylbenzenesulfonamide
0
pyridazines;
ring assembly		00low000000
N-[1-(3-fluorophenyl)-6,6-dimethyl-5,7-dihydro-4H-indazol-4-yl]-2-(2-pyridinylthio)acetamide
0
pyrazoles;
ring assembly		00low000000
N-[1-(2,3-dimethylphenyl)-4,5,6,7-tetrahydroindazol-4-yl]-2,5-dimethyl-3-pyrazolecarboxamide
0
pyrazoles;
ring assembly		00low000000
N-[1-(4-tert-butylphenyl)-4,5,6,7-tetrahydroindazol-4-yl]-4-methyl-5-thiadiazolecarboxamide
0
pyrazoles;
ring assembly		00low000000
dafadine O
0
aromatic amide;
aromatic ether;
isoxazoles;
N-acylpiperidine;
pyridines;
ring assembly		P450 inhibitor00low000000
N-[1-(3,4-dimethylphenyl)-4,5,6,7-tetrahydroindazol-4-yl]-2,5-dimethyl-3-pyrazolecarboxamide
0
pyrazoles;
ring assembly		00low000000
N-[1-(3,4-dimethylphenyl)-4,5,6,7-tetrahydroindazol-4-yl]-5-(methoxymethyl)-2-furancarboxamide
0
pyrazoles;
ring assembly		00low000000
N-[1-(3,4-dimethylphenyl)-4,5,6,7-tetrahydroindazol-4-yl]-2-(3,5-dimethyl-1-pyrazolyl)acetamide
0
pyrazoles;
ring assembly		00low000000
cep 26401
0
pyridazines;
ring assembly		00low000000
cym-5442
0
oxadiazole;
ring assembly		00low000000
4-[5-(3-chlorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid
0
oxadiazole;
ring assembly		00low000000
bms 708163
0
oxadiazole;
ring assembly		00low000000
gsk 1070916
0
pyrazoles;
ring assembly		00low000000
difenacoum
0
benzenes;
naphthalenes;
ring assembly		00low000000
bromfenacoum
0
benzenes;
naphthalenes;
ring assembly		00low000000
flocoumafen
0
benzenes;
naphthalenes;
ring assembly		00low000000
gs-5816
0
carbamate ester;
ether;
imidazoles;
L-valine derivative;
N-acylpyrrolidine;
organic heteropentacyclic compound;
ring assembly		antiviral drug;
hepatitis C virus nonstructural protein 5A inhibitor		00low000000
mk-8742
0
carbamate ester;
imidazoles;
L-valine derivative;
N-acylpyrrolidine;
organic heterotetracyclic compound;
ring assembly		antiviral drug;
hepatitis C virus nonstructural protein 5A inhibitor;
hepatoprotective agent		00low000000
N-[3-[(1,5-dimethyl-3-oxo-2-phenyl-4-pyrazolyl)amino]-1-isoindolylidene]-2-thiophenecarboxamide
0
pyrazoles;
ring assembly		00low000000
3-(4-methoxyphenyl)-1-methyl-1H-1,2,4-triazol-5-ol
0
ring assembly;
triazoles		00low000000
3-amino-2-phenyl-2H-pyrazolo[4,3-c]pyridine-4,6-diol
0
pyrazoles;
ring assembly		00low000000
4-methyl-3-phenyl-1,2-dihydropyrazolo[3,4-b]pyridin-6-one
0
pyrazoles;
ring assembly		00low000000
scytonemin
0
enone;
organic heterotricyclic compound;
organonitrogen heterocyclic compound;
polyphenol;
ring assembly		bacterial metabolite;
biological pigment;
ultraviolet filter		00low000000
5-(4-chlorophenyl)-3-(4-nitrophenyl)-1H-pyrazole
0
pyrazoles;
ring assembly		00low000000
sta 9090
0
ring assembly;
triazoles		00low000000
opicapone
0
oxadiazole;
ring assembly		00low000000
am 251
0
amidopiperidine;
carbohydrazide;
dichlorobenzene;
organoiodine compound;
pyrazoles		antidepressant;
antineoplastic agent;
apoptosis inducer;
CB1 receptor antagonist		00low000000
celecoxib
0
organofluorine compound;
pyrazoles;
sulfonamide;
toluenes		cyclooxygenase 2 inhibitor;
geroprotector;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug		00low000000
dipyrone
0
amino sulfonic acid;
pyrazoles		anti-inflammatory agent;
antipyretic;
antirheumatic drug;
cyclooxygenase 3 inhibitor;
non-narcotic analgesic;
peripheral nervous system drug;
prodrug		00low000000
fipronil
0
(trifluoromethyl)benzenes;
dichlorobenzene;
nitrile;
primary amino compound;
pyrazoles;
sulfoxide		00low000000
fomepizole
0
pyrazolesantidote;
EC 1.1.1.1 (alcohol dehydrogenase) inhibitor;
protective agent		00low000000
sulfaphenazole
0
primary amino compound;
pyrazoles;
substituted aniline;
sulfonamide antibiotic;
sulfonamide		antibacterial drug;
EC 1.14.13.181 (13-deoxydaunorubicin hydroxylase) inhibitor;
EC 1.14.13.67 (quinine 3-monooxygenase) inhibitor;
P450 inhibitor		00low000000
betazole
0
primary amino compound;
pyrazoles		diagnostic agent;
gastrointestinal drug;
histamine agonist		00low000000
5-methylpyrazole-3-carboxylic acid
0
monocarboxylic acid;
pyrazoles		metabolite00low000000
noramidopyrine
0
pyrazoles;
secondary amino compound		antipyretic;
drug metabolite;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
opioid analgesic;
peripheral nervous system drug		00low000000
metazachlor
0
aromatic amide;
organochlorine compound;
pyrazoles		environmental contaminant;
herbicide;
xenobiotic		00low000000
tepoxalin
0
aromatic ether;
hydroxamic acid;
monochlorobenzenes;
pyrazoles		antipyretic;
apoptosis inhibitor;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
immunomodulator;
lipoxygenase inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug		00low000000
n-acetylaminoantipyrine
0
acetamides;
pyrazoles		drug metabolite;
marine xenobiotic metabolite		00low000000
lonazolac
0
monocarboxylic acid;
monochlorobenzenes;
pyrazoles		antineoplastic agent;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug		00low000000
4-iodopyrazole
0
organoiodine compound;
pyrazoles		00low000000
ethyl 5-(4,6-dimethoxypyrimidin-2-ylcarbamoylsulfamoyl)-1-methylpyrazole-4-carboxylate
0
pyrazoles00low000000
halosulfuron methyl
0
pyrazoles00low000000
pyraclofos
0
monochlorobenzenes;
organic thiophosphate;
organochlorine insecticide;
organosulfur compound;
organothiophosphate insecticide;
pyrazoles		agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor		00low000000
sr141716
0
amidopiperidine;
carbohydrazide;
dichlorobenzene;
monochlorobenzenes;
pyrazoles		anti-obesity agent;
appetite depressant;
CB1 receptor antagonist		00low000000
sc 58125
0
organofluorine compound;
pyrazoles;
sulfone		antineoplastic agent;
cyclooxygenase 2 inhibitor		00low000000
birb 796
0
aromatic ether;
morpholines;
naphthalenes;
pyrazoles;
ureas		EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
immunomodulator		00low000000
1-(3-tert-butyl-1-methylpyrazol-5-yl)-3-(4-chlorophenyl)urea
0
monochlorobenzenes;
phenylureas;
pyrazoles		EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor00low000000
hts 466284
0
pyrazoles;
pyridines;
quinolines		TGFbeta receptor antagonist00low000000
3-pentyl-4,5,6,7-tetrahydro-1H-indazole
0
pyrazoles00low000000
5-(2-methylpropyl)-1H-pyrazole-3-carboxylic acid
0
pyrazoles00low000000
N-(cyclopentylideneamino)-4,5,6,7-tetrahydro-1H-indazole-3-carboxamide
0
aromatic amide;
pyrazoles		00low000000
N-(4,5-dihydrothiazol-2-yl)-1-ethyl-3-pyrazolecarboxamide
0
aromatic amide;
pyrazoles		00low000000
1-[[(1,3-dimethyl-4-pyrazolyl)-oxomethyl]amino]-3-(4-methylphenyl)thiourea
0
aromatic amide;
pyrazoles		00low000000
cct018159
0
benzodioxine;
pyrazoles;
resorcinols		antineoplastic agent;
apoptosis inducer;
Hsp90 inhibitor		00low000000
1-[4-(2-fluorophenyl)-2-thiazolyl]-5-(trifluoromethyl)-4-pyrazolecarboxylic acid ethyl ester
0
pyrazoles00low000000
2,2,2-trifluoro-N-(5-oxo-1-phenyl-4H-pyrazol-3-yl)acetamide
0
pyrazoles;
secondary carboxamide;
trifluoroacetamide		00low000000
5-chloro-1-[(2-chlorophenyl)methyl]-3-methyl-4-pyrazolecarboxylic acid [2-[(5-methyl-3-isoxazolyl)amino]-2-oxoethyl] ester
0
pyrazoles00low000000
3-(tert-butyl)-1-methyl-4,5-dihydro-1H-pyrazol-5-one
0
pyrazoles00low000000
ethyl 1-[4-(4-chlorobenzenesulfonamido)phenyl]-5-(trifluoromethyl)pyrazole-4-carboxylate
0
ethyl ester;
monochlorobenzenes;
organofluorine compound;
pyrazoles;
sulfonamide		00low000000
deracoxib
0
organofluorine compound;
pyrazoles;
sulfonamide		cyclooxygenase 2 inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug		00low000000
fipronil sulfone
0
(trifluoromethyl)benzenes;
dichlorobenzene;
nitrile;
pyrazoles;
sulfone		marine xenobiotic metabolite00low000000
sr 144528
0
bridged compound;
monochlorobenzenes;
pyrazoles;
secondary carboxamide		CB2 receptor antagonist;
EC 2.3.1.26 (sterol O-acyltransferase) inhibitor		00low000000
2-[[3-methyl-5-oxo-1-(phenylmethyl)-4H-pyrazol-4-yl]-phenylmethyl]propanedinitrile
0
pyrazoles00low000000
5-tert-butyl-4,5,6,7-tetrahydro-1H-indazole-3-carboxylic acid
0
pyrazoles00low000000
1-[2-(1-oxo-2-thiophen-2-ylethoxy)ethyl]-5-[(1-oxo-2-thiophen-2-ylethyl)amino]-4-pyrazolecarboxylic acid ethyl ester
0
pyrazoles00low000000
N1',N6'-bis[(5-methyl-1H-pyrazol-3-yl)-oxomethyl]hexanedihydrazide
0
aromatic amide;
pyrazoles		00low000000
sc 560
0
aromatic ether;
monochlorobenzenes;
organofluorine compound;
pyrazoles		angiogenesis modulating agent;
antineoplastic agent;
apoptosis inducer;
cyclooxygenase 1 inhibitor;
non-steroidal anti-inflammatory drug		00low000000
ver-49009
0
aromatic amide;
monochlorobenzenes;
monomethoxybenzene;
pyrazoles;
resorcinols		Hsp90 inhibitor00low000000
5-methyl-2-phenyl-4-propan-2-ylidene-3-pyrazolone
0
pyrazoles00low000000
1,3,5-tris(4-hydroxyphenyl)-4-propyl-1h-pyrazole
0
phenols;
pyrazoles		estrogen receptor agonist00low000000
N-(2-methoxyethyl)-2-(5-methyl-4,5,6,7-tetrahydroindazol-2-yl)acetamide
0
pyrazoles00low000000
GSK3-XIII
0
aromatic amine;
pyrazoles;
quinazolines;
secondary amino compound		EC 2.7.11.26 (tau-protein kinase) inhibitor00low000000
pyrachlostrobin
0
aromatic ether;
carbamate ester;
carbanilate fungicide;
methoxycarbanilate strobilurin antifungal agent;
monochlorobenzenes;
pyrazoles		antifungal agrochemical;
environmental contaminant;
mitochondrial cytochrome-bc1 complex inhibitor;
xenobiotic		00low000000
4-(5-(4-fluorophenyl)-3-(trifluoromethyl)-1h-pyrazol-1-yl)benzenesulfonamide
0
organofluorine compound;
pyrazoles;
sulfonamide		cyclooxygenase 2 inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug		00low000000
sd 0006
0
monochlorobenzenes;
N-acylpiperidine;
primary alcohol;
pyrazoles;
pyrimidines		00low000000
osu 03012
0
antibiotic antifungal drug;
aromatic amide;
glycine derivative;
organofluorine compound;
phenanthrenes;
pyrazoles		antineoplastic agent;
apoptosis inducer;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor		00low000000
at 7867
0
monochlorobenzenes;
piperidines;
pyrazoles		antineoplastic agent;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor		00low000000
chlorantranilipole
0
monochlorobenzenes;
organobromine compound;
pyrazole insecticide;
pyrazoles;
pyridines;
secondary carboxamide		ryanodine receptor agonist00low000000
at 7519
0
dichlorobenzene;
piperidines;
pyrazoles;
secondary carboxamide		antineoplastic agent;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor		00low000000
penthiopyrad
0
aromatic amide;
organofluorine compound;
pyrazoles;
thiophenes		00low000000
azd 1152
0
anilide;
monoalkyl phosphate;
monofluorobenzenes;
pyrazoles;
quinazolines;
secondary amino compound;
secondary carboxamide;
tertiary amino compound		antineoplastic agent;
Aurora kinase inhibitor;
prodrug		00low000000
5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]pyrazole-4-carboxamide
0
aromatic amide;
organofluorine compound;
pyrazoles		00low000000
GDC-0879
0
indanes;
ketoxime;
primary alcohol;
pyrazoles;
pyridines		antineoplastic agent;
B-Raf inhibitor		00low000000
azd 1152-hqpa
0
anilide;
monofluorobenzenes;
primary alcohol;
pyrazoles;
quinazolines;
secondary amino compound;
secondary carboxamide;
tertiary amino compound		antineoplastic agent;
Aurora kinase inhibitor		00low000000
fluxapyroxad
0
anilide fungicide;
aromatic amide;
biphenyls;
pyrazoles;
trifluorobenzene		antifungal agrochemical;
EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor		00low000000
cyenopyrafen
0
nitrile;
pivalate ester;
pyrazoles		agrochemical;
proacaricide		00low000000
sgx 523
0
aryl sulfide;
biaryl;
pyrazoles;
quinolines;
triazolopyridazine		c-Met tyrosine kinase inhibitor;
nephrotoxic agent		00low000000
bms 754807
0
pyrazoles;
pyridines;
pyrrolidines;
pyrrolotriazine		antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor		00low000000
dcc-2036
0
organofluorine compound;
phenylureas;
pyrazoles;
pyridinecarboxamide;
quinolines		tyrosine kinase inhibitor00low000000
incb-018424
0
nitrile;
pyrazoles;
pyrrolopyrimidine		antineoplastic agent;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor		00low000000
baricitinib
0
azetidines;
nitrile;
pyrazoles;
pyrrolopyrimidine;
sulfonamide		anti-inflammatory agent;
antirheumatic drug;
antiviral agent;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
immunosuppressive agent		00low000000
gsk-5498a
0
(trifluoromethyl)benzenes;
difluorobenzene;
pyrazoles;
secondary carboxamide		calcium channel blocker00low000000
azd4547
0
benzamides;
N-arylpiperazine;
pyrazoles		fibroblast growth factor receptor antagonist00low000000
N-[9-(dichloromethylene)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-3-(difluoromethyl)-1-methylpyrazole-4-carboxamide
0
aromatic amide;
bridged compound;
olefinic compound;
organochlorine compound;
organofluorine compound;
pyrazoles		00low000000
3-(difluoromethyl)-N-methoxy-1-methyl-N-[1-(2,4,6-trichlorophenyl)propan-2-yl]pyrazole-4-carboxamide
0
aromatic amide;
monocarboxylic acid amide;
organofluorine compound;
pyrazoles;
trichlorobenzene		00low000000
oxathiapiprolin
0
1,3-thiazoles;
isoxazoline;
N-acylpiperidine;
organofluorine compound;
pyrazoles;
tertiary carboxamide		00low000000
LimKi 3
0
1,3-thiazoles;
dichlorobenzene;
organofluorine compound;
pyrazoles;
secondary carboxamide		LIM kinase inhibitor00low000000
pf-06463922
0
aminopyridine;
aromatic ether;
azamacrocycle;
benzamides;
cyclic ether;
monofluorobenzenes;
nitrile;
organic heterotetracyclic compound;
pyrazoles		antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor		00low000000
CCT251545
0
azaspiro compound;
chloropyridine;
pyrazoles		antineoplastic agent;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor;
Wnt signalling inhibitor		00low000000
ldc4297
0
aromatic ether;
piperidines;
pyrazoles;
pyrazolotriazine;
secondary amino compound		antineoplastic agent;
antiviral agent;
apoptosis inducer;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor		00low000000
praliciguat
0
aminopyrimidine;
isoxazoles;
monofluorobenzenes;
organofluorine compound;
pyrazoles;
secondary amino compound;
tertiary alcohol		anti-inflammatory agent;
antihypertensive agent;
soluble guanylate cyclase activator;
vasodilator agent		00low000000
can 508
0
aromatic amine;
monoazo compound;
phenols;
pyrazoles		angiogenesis inhibitor;
antineoplastic agent;
apoptosis inducer;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor		00low000000
pyrazofurin
0
C-glycosyl compound;
pyrazoles		antimetabolite;
antimicrobial agent;
antineoplastic agent;
EC 4.1.1.23 (orotidine-5'-phosphate decarboxylase) inhibitor		00low000000
hydrazinocurcumin
0
aromatic ether;
olefinic compound;
polyphenol;
pyrazoles		angiogenesis modulating agent;
antineoplastic agent;
EC 2.3.1.48 (histone acetyltransferase) inhibitor;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor		00low000000
ConditionIndicatedStudiesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
Inflammation0
1
2010201014.0high000100
Innate Inflammatory Response0
1
2010201014.0high000100